Totally anecdotal from me but here goes....
My YJ has 220K miles on it, at 150K I had a race engine mechanic rebuild it.
After 150K miles of shifting at redline, and often way past redline,
The only really worn parts were the rings, main and rod bearings. Bores valves pistons looked great.
I really drive hard I regularly tow a small trailer and pull long passes at 3500 to 4200 rpm.
I have run Synthetic oil most of the jeeps life...
I usually run 87 octane gas. Unless its over 75 degrees out then I jump to premium.
I have had 4.56 gears since about 12K miles.
My rule of thumb is you cruise at about 60% of the redline of the engine and your fine.
I wish I had done 4.88 becasue 5th is still a little marginal on the high way on 33" tires,
I recently down stepped to 32's and it runs great and gets a bit better mileage.
Thats my twist on it...
Dave